Transitional cell carcinoma (urinary bladder) | Radiology Reference Article | Radiopaedia.org (2024)

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Transitional cell carcinoma (urinary bladder) | Radiology Reference Article | Radiopaedia.org (2024)

FAQs

What is a transitional cell carcinoma of the urinary bladder? ›

Urothelial carcinoma (also called transitional cell carcinoma) is cancer that begins in the urothelial cells, which line the urethra, bladder, ureters, renal pelvis, and some other organs. Almost all bladder cancers are urothelial carcinomas.

Is TCC benign or malignant? ›

Transitional cell carcinoma (TCC), also called urothelial cell carcinoma (UCC), is the most common primary malignancy of the urinary tract and may be found along its entire length, from the renal pelvis to the bladder.

What is the difference between TCC and RCC cancer? ›

Background: Renal cell carcinoma (RCC) originates from the renal parenchyma, whereas transitional cell carcinoma (TCC) originates from the renal urothelium.

What is the most common malignancy of the urinary bladder is TCC transitional cell carcinoma? ›

Greater than 90% of urinary tract cancers are transitional cell carcinomas (TCC) known today as urothelial carcinomas (UC). [1] Rarer cancers include squamous cell carcinoma, small cell carcinoma, and adenocarcinoma. Benign neoplasms are also sometimes seen.

How serious is transitional cell carcinoma of the bladder? ›

If it's high grade, it's more likely to spread to deeper layers of your bladder, other areas of your body, and your lymph nodes. It's also likely to come back after treatment. High-grade TCC is the type of bladder cancer that is more likely to be life-threatening.

What is the survival rate for transitional cell carcinoma of the bladder? ›

If the cancer extends through the bladder to the surrounding tissue or has spread to nearby lymph nodes or organs, the five-year survival rate is 39%. If the cancer has spread to distant parts of the body, the five-year survival rate is 8%.

How long do you live with transitional cell carcinoma? ›

Results: The actuarial 5-year overall and disease specific survival for patients with stage III disease was 28 and 40%, respectively. Median disease specific survival was 37 months. Median overall and disease specific survival for patients with stage IV disease was 7 months.

How quickly does TCC grow? ›

TCC is slow growing and usually has no symptoms in the early stages. When symptoms do develop, they may include painful urination, blood in the urine, fatigue, and weight loss. Smoking is one of the largest risk factors for TCC.

How do you treat transitional cell carcinoma of the bladder? ›

Bladder cancer is sometimes treated with external beam radiation therapy. This type of radiation therapy uses a machine outside the body to send radiation toward the area of the body with cancer. Radiation therapy may be given alone or with other types of treatment, such as chemotherapy.

Is TCC an aggressive cancer? ›

This disease detracts from quality of life and takes the lives of more than 16,000 people each year. Most deaths are due to the more aggressive form of bladder cancer, high grade, invasive transitional cell carcinoma (TCC).

What is the new name for transitional cell carcinoma? ›

Urothelial (transitional cell) bladder cancer

About 90 out of 100 bladder cancers in the UK (about 90%) are urothelial cancer. These are also called transitional cell cancer. Urothelial cancer develops from the cells of the bladder lining (urothelium). These are called transitional or urothelial cells.

What is the most common metastasis of TCC? ›

Transitional cell carcinoma (TCC) of the bladder commonly metastasizes to the pelvic lymph nodes, lungs, liver, bones, adrenals, or brain. Unusual sites include the heart, kidney, spleen, pancreas, and reproductive system.

What is the primary symptom of transitional cell carcinoma of the bladder? ›

Symptoms of this type of cancer include: Blood in the urine. Back pain. Cramps in the side or back.

What is a risk factor for transitional cell carcinoma of the bladder? ›

Factors that may increase bladder cancer risk include: Smoking. Smoking cigarettes, cigars or pipes may increase the risk of bladder cancer by causing harmful chemicals to accumulate in the urine. When you smoke, your body processes the chemicals in the smoke and excretes some of them in your urine.

What symptoms are typically associated with transitional cell carcinoma of the bladder? ›

Other bladder cancer symptoms include:
  • Visible blood in your pee (hematuria): Healthcare providers can also spot microscopic amounts of blood in pee when they do a urinalysis.
  • Pain when you pee (dysuria): This is a burning or stinging sensation that you may feel when you start to pee or after you pee.
Aug 26, 2022

Is transitional cell carcinoma of the bladder curable? ›

It's helpful to get an early diagnosis of transitional cell cancer of the renal pelvis and ureter because the disease is highly curable when it's treated before it spreads. After treatment, patients should continue to see their doctor regularly to monitor the possible recurrence of the cancer.

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