Stages of renal pelvis and ureter cancer (2024)

FAQs

What is the staging system for renal pelvis urothelial carcinoma? ›

The most common staging system for renal pelvis and ureter cancer is the TNM system. For renal pelvis and ureter cancer there are 5 stages – stage 0 followed by stages 1 to 4. Often the stages 1 to 4 are written as the Roman numerals I, II, III and IV.

Stages of Ureter Cancer

Localized cancer remains at the point of origin, and has not spread beyond the kidney or ureter. Regional cancer has progressed into the tissue surrounding the kidney and/or neighboring lymph nodes, while metastatic cancer has invaded other parts of the body.

Stage III (also called stage 3)

In stage III, cancer has spread: from the muscle layer of the renal pelvis to fat around the renal pelvis or to tissue in the kidney; or. from the muscle layer of the ureter to fat around the ureter.

Flat urothelial carcinomas are tumours that grow along the lining of the renal pelvis or ureter. They are high grade and more likely to grow deeper into the layers of the renal pelvis or ureter wall. Non-invasive flat urothelial carcinoma is more commonly called carcinoma in situ (CIS).

A radical nephroureterectomy is the most common surgery done for cancer of the renal pelvis or ureter. The surgeon removes the entire kidney, all of the ureter and the tissue where the ureter connects to the bladder (called the bladder cuff).

If bladder cancer has spread to the regional lymph nodes, the 5-year survival rate is 39.2%. If it has spread to a distant site, the 5-year survival rate is 8.3%.

Low-grade UTUC is less aggressive. It is less likely to invade deeper into the kidney or to spread to other parts of the body. High-grade UTUC is more likely to invade the kidney itself or other organs. It is more likely to spread to other parts of the body.

The 5-year relative survival rate of people with bladder cancer that has not spread beyond the inner layer of the bladder wall is 96%. Almost half of people are diagnosed with this stage. If the tumor is invasive but has not yet spread outside the bladder, the 5-year relative survival rate is 70%.

These cancers are curable in more than 90% of patients if they are superficial and confined to the renal pelvis or ureter.

Signs and symptoms of ureteral cancer include: Blood in urine. Back pain. Pain when urinating.

Is cancer of ureter fatal? ›

Outcome varies, depending on the location of the tumor and whether the cancer has spread. Cancer that is only in the kidney or ureter may be cured with surgery. Cancer that has spread to other organs is usually not curable.

If the cancer has reached the lymph nodes, they may be surgically removed. The five-year survival rate for stage 3 kidney cancer is 53 percent . That means that out of 100 people, 53 people diagnosed with stage 3 kidney cancer will still be living five or more years after being diagnosed.

Around 75 out of 100 people (around 75%) with stage 3 kidney cancer will survive their cancer for 5 years or more after they're diagnosed. Around 15 out of 100 people (around 15%) with stage 4 kidney cancer will survive their cancer for 5 years or more after they're diagnosed.

Stage II: The cancer has grown into the muscle behind the inner lining of the renal pelvis or ureter. The cancer has not spread to the lymph nodes or other parts of the body (T2, N0, M0). Stage III: The cancer has grown past the muscle and into the fat surrounding the kidney or ureter or into the renal parenchyma.

Stage II may also be described as muscle-invasive bladder cancer. In stage II, cancer has spread through the connective tissue into the muscle layers of the bladder. Stage II bladder cancer (muscle-invasive bladder cancer). Cancer has spread through the connective tissue into the muscle layers of the bladder.

Renal Cell Carcinoma makes up 95% of kidney tumors. Less common types of cancerous tumors in the kidney include: Urothelial Carcinoma: arise from the renal pelvis and resemble bladder cancer cells.

Stage 0 bladder cancer (noninvasive bladder cancer). Cancer cells are found in tissue lining the inside of the bladder but have not invaded into the bladder wall. Stage 0a (also called noninvasive papillary carcinoma) may look like long, thin growths extending into the bladder lumen (the space where urine collects).