Prognosis and Life Expectancy for Stage 4 Bladder Cancer (2024)

If bladder cancer has spread to the regional lymph nodes, the 5-year survival rate is 39.2%. If it has spread to a distant site, the 5-year survival rate is 8.3%.

Receiving a diagnosis of stage 4 bladder cancer can feel overwhelming.

Many cancer treatments can be challenging. However, treatment can reduce or even eliminate your symptoms and help you live a longer, more comfortable life.

That said, it’s important to consider the pros and cons of treating stage 4 bladder cancer because treatments have side effects and risks.

Read on to learn more about stage 4 bladder cancer and how it’s managed.

Stage 4 bladder cancer is also called metastatic bladder cancer. This means the cancer has spread outside the bladder into other areas.

It is the most advanced stage, and the outlook is less promising than in earlier stages.

Symptoms of bladder cancer can include:

  • blood or blood clots in your urine
  • pain or burning during urination
  • frequent urination
  • needing to urinate at night
  • needing to urinate but not being able to
  • lower back pain on one side of the body

These symptoms commonly lead to a diagnosis, but they aren’t unique to stage 4 bladder cancer.

People with metastatic cancer may experience symptoms relating to where the cancer has spread. For example, if bladder cancer has spread to the lungs, they may experience chest pain or increased coughing.

Metastatic bladder cancer is difficult to control because it has already traveled to other parts of the body. The later you receive a diagnosis and the farther the cancer has traveled, the less chance it can be controlled.

For bladder cancer, if the cancer has spread to the regional lymph nodes, the 5-year survival rate is 39.2%. If it has spread to a distant site, the 5-year survival rate is 8.3%.

These percentages of people will survive for 5 years after diagnosis compared to those who do not have bladder cancer, and the rates improved slightly over time.

There are still treatment options for this stage that help control the cancer for as long as possible. This includes chemotherapy, immunotherapy, radiation, and surgery. Keep in mind that new treatments are always in development.

While receiving treatment, people can also receive palliative care to help manage their symptoms and maximize their quality of life.

You may be able to join a clinical trial. Trials may study the effectiveness of new therapies and combinations, such as adding new anticancer or immunotherapy drugs to other therapies. Sometimes, they may be paid for.

Prognosis and treatment options rely heavily on the details of each person’s disease and overall health.

Does chemo work for stage 4 bladder cancer?

Chemotherapy is part of the treatment a person with stage 4 bladder cancer receives. Its effectiveness, however, depends on the person and their specific cancer.

How aggressive is bladder cancer?

Bladder cancer can be aggressive. That said, it is less likely to be aggressive than many other cancers. Research shows that when it first manifests, about 70% of people will have a non-invasive form.

Where is the first place bladder cancer spreads?

If bladder cancer spreads, it usually affects the organs closer to the bladder first. This includes the urethra, prostate, and vagin*.

Knowing cancer grade and other details can help better predict prognosis, treatment options, and life expectancy.

Of course, these survival rates and numbers are only estimates. They can’t predict what will happen to every person. Some people will live longer or shorter than these estimated rates.

Reading them can be confusing and may lead to more questions. Be sure to talk openly with your healthcare professionals to better understand your situation.

Prognosis and Life Expectancy for Stage 4 Bladder Cancer (2024)

FAQs

Prognosis and Life Expectancy for Stage 4 Bladder Cancer? ›

If bladder cancer has spread to the regional lymph nodes, the 5-year survival rate is 39.2%. If it has spread to a distant site, the 5-year survival rate is 8.3%.

What is the life expectancy of someone with stage 4 bladder cancer? ›

For a person with stage 4 bladder cancer, the 5-year relative survival rate is around 5 percent . This means that the person is 5 percent as likely as someone without cancer to live for a minimum of 5 years after diagnosis.

How fatal is bladder cancer? ›

Survival for all stages of bladder cancer

more than 50 out of every 100 (more than 50%) survive their cancer for 5 years or more after they are diagnosed. around 45 out of every 100 (around 45%) survive their cancer for 10 years or more after diagnosis.

What is the mortality rate for bladder cancer by age? ›

Among patients over 85 years of age, the survival rate was only 40.0%, much lower than the 83.4% among young patients (≤54 years old). Among bladder cancer patients aged over 85 years, the proportion of deaths from other causes was greater than the deaths from this cancer (32.5% vs 27.5%) (Table 1).

What is the prognosis for bladder cancer in the elderly? ›

In a study from the United States Surveillance, Epidemiology, and End Results (SEER) database, five-year survival rates declined progressively from 84 percent in those between 65 and 69 years to 60 percent in those 85 and older [3]. Age is a risk factor for the development of bladder cancer.

Is stage 4 bladder cancer a terminal? ›

Stage 4 bladder cancer survival rate

The five-year relative survival rate for patients with metastatic bladder cancer, where cancer cells have spread to distant parts of the body, is 8 percent.

What to expect when dying from bladder cancer? ›

The dying person will feel weak and sleep a lot. When death is very near, you might notice some physical changes such as changes in breathing, loss of bladder and bowel control and unconsciousness. It can be emotionally very difficult to watch someone go through these physical changes.

What organ does bladder cancer spread to first? ›

Bladder cancer is most likely to spread to the structures close to the bladder, such as the ureters, urethra, prostate, vagin*, or into the pelvis. This is called local spread or locally advanced cancer.

Does bladder cancer progress quickly? ›

low grade – the cancer cells are usually slow-growing. Most bladder tumours are low grade. high grade – the cancer cells look very abnormal and grow quickly.

What are the signs that bladder cancer is getting worse? ›

If bladder cancer reaches an advanced stage and begins to spread, symptoms can include:
  • pelvic pain.
  • bone pain.
  • unintentional weight loss.
  • swelling of the legs.
Nov 13, 2023

What is the longest survival rate for bladder cancer? ›

5-year relative survival rates for bladder cancer
SEER Stage5-year Relative Survival Rate
In situ alone Localized96% 71%
Regional39%
Distant8%
All SEER stages combined78%
Jan 17, 2024

Is bladder cancer usually terminal? ›

Survival rates for bladder cancer

For example, the 5-year relative survival rate for localized bladder cancer is 71%. This means that people diagnosed with localized bladder cancer are 71% as likely as someone who does not have bladder cancer to be alive 5 years after diagnosis.

How long does it take for bladder cancer to metastasis? ›

It typically doesn't spread very quickly. However, other types of bladder cancer, such as adenocarcinoma, squamous cell carcinoma, and small cell carcinoma, spread much faster. In most cases, treatment, if started early enough, can prevent the spread of bladder cancer.

Is chemo worth it for bladder cancer? ›

It can lower the risk of bladder cancer coming back in the future. Chemotherapy after surgery may help to stop the cancer coming back.

What are the odds of beating bladder cancer? ›

The 5-year relative survival rate of people with bladder cancer that has not spread beyond the inner layer of the bladder wall is 96%. Almost half of people are diagnosed with this stage. If the tumor is invasive but has not yet spread outside the bladder, the 5-year relative survival rate is 70%.

What is the quality of life with bladder cancer? ›

Discussion. In this review, the QOL among patients was estimated at 53.92 (95% CI: 47.84 to 60). We also found that physical domains of QOL were significantly affected by diagnosis or treatment procedures of the disease and were worse in terms of role limitations due to physical health and social functioning.

What happens when you have stage 4 bladder cancer? ›

Stage 4 is advanced bladder cancer. It is metastatic bladder cancer, or cancer that has spread to distant lymph nodes or organs. Stage 4 also includes cancer that has spread outside your bladder into the wall of your abdomen or pelvis.

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